For what it's worth, I just hit my first snag with the Windows 10 Anniversary Update. It broke Quickbooks Enterprise 11 for one of my clients. Not only would it not run, but I was also unable to reinstall the software. It hung at about the 10 or 15% mark. Perhaps a newer version of this software might have worked, but when my client bought it the first time around it was about $2400, so it was way cheaper to remove the Anniversary Update.